… and when it becomes a rhodopsin + rod. We show that FCS arrests rod development in
these cultures at a postmitotic, rhodopsin − , pre-rod stage. We present evidence that FCS acts …

… calf serum (PCS) in these cultures arrests rod differentiation at a postmitotic, pre-rod stage of
… cells, which is mediated by leukaemia inhibitory factor (LIT). The … Müller cell-derived LIF …

… LIF can inhibit functional maturation of rod photoreceptors. LIF … This age represents the most
active period of cell death in rd-Imice (… In addition, the photoreceptors failed to develop outer …

… In the initial phase, dividing progenitors become postmitotic … In development, cells in the
photoreceptor lineage turn on … step for the expression of both rod and cone photoreceptor genes. …

… The stages of rod photoreceptor differentiation are shown along with … Muller-cell-derived
leukaemia inhibitory factor arrests rod photoreceptor differentiation at a postmitotic pre-rod stage …

… One hallmark of such inhibitory factors is that they do not … of postmitotic neurons or glial cells
occurs over a protracted … and promote the differentiation of glial cells at the expense of rod …

… factor (CNTF) and leukemia inhibitory factor (LIF) negatively regulate the development of
rod photoreceptors … of rod photoreceptor differentiation, we used a specific inhibitor of MAPK …

The development of the nervous system is guided by a balanced action between intrinsic
factors represented by the genetic program and epigenetic factors characterized by cell-cell …

… in progenitor cells then in postmitotic precursors of the INL … rod differentiation and promotes
bipolar cell production, similar to effects of exogenous CNTF and leukemia inhibitory factor (…

… ), IL‐11, leukemia inhibitory factor, and oncostatin M. The effects … early, postmitotic
photoreceptors into rod photoreceptors that … Once we have developed in vitro differentiation …